abstract：:Susceptibility breakpoints provide fundamental information for rational administration of antibiotics. The present investigation reports the first valnemulin susceptibility breakpoint (MIC<0.25 μg/mL) against Clostridium perfringens infections in rabbits based on the wild-type cutoff (COWT) and the pharmacokinetics/ph...

journal_title：Anaerobe

authors： Tao MT,Zhou YF,Sun J,Liu YH,Liao XP

更新日期：2017-12-01 00:00:00

abstract：:Clostridium difficile is a Gram-positive spore forming anaerobic bacterium and the main cause of healthcare-associated diarrhea. This study aimed to perform the phenotypic characterization and molecular typing of Clostridium difficile isolates among patients at a cancer hospital in Brazil. During 18 months, 48 diarrhe...

journal_title：Anaerobe

authors： Costa CL,Mano de Carvalho CB,González RH,Gifoni MAC,Ribeiro RA,Quesada-Gómez C,Brito GAC

更新日期：2017-12-01 00:00:00

abstract：:Despite extensive research on the epidemiology of pathogenic clostridia in dogs and cats, most published studies focus on a selected animal population and/or a single veterinary medical centre. We assessed the burden of Clostridium perfringens and C. difficile shedding by small animals in 17 veterinary clinics located...

journal_title：Anaerobe

authors： Álvarez-Pérez S,Blanco JL,Harmanus C,Kuijper EJ,García ME

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to investigate Clostridium difficile and Clostridium perfringens in 82 diarrheic dogs positive for canine parvovirus type 2 (CPV). Enterotoxigenic C. perfringens type A was isolated from three (3.6%) dogs. One (1.2%) strain was also positive for NetE- and NetF-encoding genes, which are common...

journal_title：Anaerobe

authors： Silva ROS,Dorella FA,Figueiredo HCP,Costa ÉA,Pelicia V,Ribeiro BLD,Ribeiro MG,Paes AC,Megid J,Lobato FCF

更新日期：2017-12-01 00:00:00

abstract：:Cutibacterium (formerly Propionibacterium) acnes is involved in chronic/low-grade pathologies such as sarcoidosis or prosthetic joint infection (PJI). In these diseases, granulomatous structures are frequently observed. In this study, we induced a physiological granulomatous reaction in response to different well-char...

journal_title：Anaerobe

authors： Aubin GG,Ada Da Silva G,Eishi Y,Jacqueline C,Altare F,Corvec S,Asehnoune K

更新日期：2017-12-01 00:00:00

abstract：:Treponemes occur in the microflora of the dental plaque. Certain Treponema species that are frequently isolated from chronic periodontitis lesions are involved in its initiation and progression. In addition to mechanical instrumentation, antimicrobial agents are used as an adjunctive treatment modality for periodontit...

journal_title：Anaerobe

authors： Okamoto-Shibayama K,Sekino J,Yoshikawa K,Saito A,Ishihara K

更新日期：2017-12-01 00:00:00

abstract：:The recognition of the pathogenicity of Cutibacterium acnes in implant-associated infection is not always obvious. In this paper, we aimed to distinguish pathogenic and non-pathogenic C. acnes isolates. To reach this goal, we investigated the clonal complex (CC) of a large collection of C. acnes clinical isolates thro...

journal_title：Anaerobe

authors： Aubin GG,Lavigne JP,Foucher Y,Dellière S,Lepelletier D,Gouin F,Corvec S

更新日期：2017-10-01 00:00:00

abstract：:Eggerthella lenta is increasingly found in patients with severe comorbidities. Because oncologic patients are exposed to emerging pathogens, we aimed to describe the factors associated with E. lenta bacteremia in this immunosuppressed population. Oncology patients with blood cultures positive for E. lenta were retrosp...

journal_title：Anaerobe

authors： Woerther PL,Antoun S,Chachaty E,Merad M

更新日期：2017-10-01 00:00:00

abstract：:The aim of our study was to determined antimicrobial susceptibility profiles of 2673 clinically significant anaerobic bacteria belonging to the major genera, isolated in 2015 in a large tertiary-care hospital in Slovenia. The species identification was performed by MALDI-TOF mass spectrometry. Antimicrobial susceptibi...

journal_title：Anaerobe

authors： Jeverica S,Kolenc U,Mueller-Premru M,Papst L

更新日期：2017-10-01 00:00:00

abstract：:Complex microbial communities are the functional core of anaerobic digestion processes taking place in biogas plants (BGP). So far, however, a comprehensive characterization of the microbiomes involved in methane formation is technically challenging. As an alternative, enriched communities from laboratory-scale experi...

journal_title：Anaerobe

authors： Kohrs F,Heyer R,Bissinger T,Kottler R,Schallert K,Püttker S,Behne A,Rapp E,Benndorf D,Reichl U

更新日期：2017-08-01 00:00:00

abstract：:The changing epidemiology of Clostridium difficile infection over the past decades presents a significant challenge in the management of C. difficile associated diseases. The gastrointestinal tract microbiota provides colonization resistance against C. difficile, and growing evidence suggests that gut microbial derive...

journal_title：Anaerobe

authors： Thanissery R,Winston JA,Theriot CM

更新日期：2017-06-01 00:00:00

abstract：:Clostridium difficile is a spore-forming anaerobic intestinal pathogen that causes Clostridium difficile infection (CDI). C. difficile is the leading cause of toxin-mediated nosocomial antibiotic-associated diarrhea. The pathogenesis of CDI is attributed to two major virulence factors, TcdA and TcdB toxins, that cause...

journal_title：Anaerobe

authors： Ferreira TG,Moura H,Barr JR,Pilotto Domingues RMC,Ferreira EO

更新日期：2017-06-01 00:00:00

abstract：:We present the first case report of osteomyelitis due to Clostridium hydrogeniformans in a previously healthy 18-year-old male. He was admitted to our hospital because of an open contaminated fracture of the right arm after being blown into a drain in a motorbike accident. He underwent surgical debridement and treatme...

journal_title：Anaerobe

authors： Hirai J,Sakanashi D,Huh JY,Suematsu H,Hagihara M,Kato H,Yamagishi Y,Fujita J,Mikamo H

更新日期：2017-06-01 00:00:00

abstract：:Due to increasing antibiotic resistance among anaerobic bacteria, routine antimicrobial susceptibility testing is recommended by the Clinical and Laboratory Standards Institute (CLSI). This study compared the minimum inhibitory concentrations (MICs) from 920 Clostridium difficile isolates tested against seven antimicr...

journal_title：Anaerobe

authors： Hastey CJ,Dale SE,Nary J,Citron D,Law JH,Roe-Carpenter DE,Chesnel L

更新日期：2017-04-01 00:00:00

abstract：:The microbiota of the gut has many crucial functions in human health. Dysbiosis of the microbiota has been correlated to a large and still increasing number of diseases. Recent studies have mostly focused on analyzing the associations between disease and an aberrant microbiota composition. Functional studies using (in...

journal_title：Anaerobe

authors： von Martels JZH,Sadaghian Sadabad M,Bourgonje AR,Blokzijl T,Dijkstra G,Faber KN,Harmsen HJM

更新日期：2017-04-01 00:00:00

abstract：:Here, we report a case of fatal sepsis resulting from an intra-abdominal infection caused by a Bacteroides fragilis strain containing a CfiA4 metallo-β-lactamase and an upstream insertion sequence (IS) element. Meropenem was used as empiric therapy for septic shock as a result of the intra-abdominal infection, althoug...

journal_title：Anaerobe

authors： Nakamura I,Aoki K,Miura Y,Yamaguchi T,Matsumoto T

更新日期：2017-04-01 00:00:00

abstract：:The objective of this study was to assess antibiotic susceptibility among predominant Gram-negative anaerobic bacteria isolated from periodontitis patients who 5 years prior had been subject to mechanical therapy with or without adjunctive metronidazole. One pooled sample was taken from the 5 deepest sites of each of ...

journal_title：Anaerobe

authors： Dahlen G,Preus HR

更新日期：2017-02-01 00:00:00

abstract：:Recent surveys indicate that the majority of toxigenic Clostridium difficile strains isolated in European hospitals belonged to PCR-ribotypes (RTs) different from RT 027 or RT 078. Among these types, RT 018 has been reported in Italy and, more recently, in Korea and Japan. In Italy, strains RT 018 have become predomin...

journal_title：Anaerobe

authors： Barbanti F,Spigaglia P

更新日期：2016-12-01 00:00:00

abstract：:This review focuses on the virulence arsenal of the most pathogenic species among Gram positive anaerobic cocci, Finegoldia magna according to recently published data from 2012 to 2016. Virulence factors like sortase dependent pili and F. magna adhesion factor (FAF) facilitate the start of the infection. Albumin bindi...

journal_title：Anaerobe

authors： Boyanova L,Markovska R,Mitov I

更新日期：2016-12-01 00:00:00

abstract：:With the aim of elucidating the mechanisms of fluoroquinolones resistance in Propionibacterium acnes, we determined the susceptibility of fluoroquinolones in 211 isolates from patients with acne vulgaris. We identified five isolates (2.4%) with reduced susceptibility to nadifloxacin (minimum inhibitory concentration ≥...

journal_title：Anaerobe

authors： Nakase K,Sakuma Y,Nakaminami H,Noguchi N

更新日期：2016-12-01 00:00:00

abstract：:Bacterial pathogens have adopted numerous mechanisms for acquiring iron from host proteins during an infection, including the direct acquisition of ferric iron from heme-associated proteins or from iron-scavenging siderophores. Ferric iron then is transported into the cytosol, where it can be utilized by the bacterial...

journal_title：Anaerobe

authors： Awad MM,Cheung JK,Tan JE,McEwan AG,Lyras D,Rood JI

更新日期：2016-10-01 00:00:00

abstract：:Clostridium difficile is the major cause of nosocomial diarrhea. We have previously demonstrated that in southern Taiwan, severe C. difficile-associated diarrhea (CDAD) cases were due to the C. difficile RT 126 strain infection, indicating the arrival of an epidemic C. difficile clone in southern Taiwan. RT126 has a c...

journal_title：Anaerobe

authors： Tsai BY,Ko WC,Chen TH,Wu YC,Lan PH,Chen YH,Hung YP,Tsai PJ

更新日期：2016-10-01 00:00:00

abstract：:Bacteroides fragilis is a commensal bacterium found in the gut of most humans, however enterotoxigenic B. fragilis strains (ETBF) have been associated with diarrhoea and colorectal cancer (CRC). The purpose of this study was to establish a method of screening for the Bacteroides fragilis toxin (bft) gene in stool samp...

journal_title：Anaerobe

authors： Keenan JI,Aitchison A,Purcell RV,Greenlees R,Pearson JF,Frizelle FA

更新日期：2016-08-01 00:00:00

abstract：:The purpose of this study was to measure the effect of combined culture of Propionibacterium acnes and Staphylococcus aureus on biofilm formation under different oxygen concentrations. We measured planktonic growth and biofilm formation of P. acnes and S. aureus alone and together under aerobic and anaerobic condition...

journal_title：Anaerobe

authors： Tyner H,Patel R

更新日期：2016-08-01 00:00:00

abstract：:We report an extremely rare case of Porphyromonas gingivalis causing brain abscess in a patient with recurrent periodontitis. The patient presented with right-sided homonymous hemianopsia and right hemiparesis. Emergent surgical drainage was performed and antibiotics were administered. P. gingivalis was identified fro...

journal_title：Anaerobe

authors： Rae Yoo J,Taek Heo S,Kim M,Lee CS,Kim YR

更新日期：2016-06-01 00:00:00

abstract：:We present a simple protocol for the cost- and time-efficient profiling of methanogens based on T-RFLP fingerprinting of mcrA amplicons. Sequence data were compiled from mesophilic lab-scale and full-scale biogas reactors operated under various conditions and fed with various substrates. The database facilitates the r...

journal_title：Anaerobe

authors： Bühligen F,Lucas R,Nikolausz M,Kleinsteuber S

更新日期：2016-06-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and periodontitis (PD) are chronic inflammatory disorders that cause bone loss. PD tends to be more prevalent and severe in RA patients. Previous experimental studies demonstrated that RA triggers alveolar bone loss similarly to PD. The aim of this study was to investigate if arthritis-induce...

journal_title：Anaerobe

authors： Corrêa JD,Saraiva AM,Queiroz-Junior CM,Madeira MF,Duarte PM,Teixeira MM,Souza DG,da Silva TA

更新日期：2016-06-01 00:00:00

abstract：:Clostridium perfringens isolates associated with food poisoning carries a chromosomal cpe gene, while non-foodborne human gastrointestinal disease isolates carry a plasmid cpe gene. The enterotoxigenic strains tested produced vegetative cells and spores with significantly higher resistance than non-enterotoxigenic str...

journal_title：Anaerobe

authors： Abbona CC,Stagnitta PV

更新日期：2016-06-01 00:00:00

abstract：:Lifestyle and dietary habits are crucial features that can alter the gut microbiome of humans. Humans, along with their gut microbes, have coevolved in order to sustain themselves in different environments. They were able to adapt themselves to the dietary sources available in their environment. The relation between h...

journal_title：Anaerobe

authors： Anwesh M,Kumar KV,Nagarajan M,Chander MP,Kartick C,Paluru V

更新日期：2016-06-01 00:00:00

abstract：:Fusobacterium nucleatum is a strictly anaerobic, Gram negative bacterial species that has been associated with dental infections, pre-term labor, appendicitis, inflammatory bowel disease, and, more recently, colorectal cancer. The species is unusual in its phenotypic and genotypic heterogeneity, with some strains demo...

journal_title：Anaerobe

authors： Cochrane K,McGuire AM,Priest ME,Abouelleil A,Cerqueira GC,Lo R,Earl AM,Allen-Vercoe E

更新日期：2016-04-01 00:00:00

abstract：CONTEXT:Clostridium difficile infection (CDI) produces a variety of clinical presentations ranging from mild diarrhea to severe infection with fulminant colitis, septic shock, and death. Over the past decade, the emergence of the BI/NAP1/027 strain has been linked to higher prevalence and severity of CDI. The guideline...

journal_title：Anaerobe

authors： Khanafer N,Barbut F,Eckert C,Perraud M,Demont C,Luxemburger C,Vanhems P

更新日期：2016-02-01 00:00:00

abstract：:Recently new resin-based BacT/Alert FAN Plus bottles containing antibiotic-binding polymeric beads, were introduced as an improvement of the charcoal-based FAN bottles for the recovery of bacteria and fungi. To assess the performance of the novel anaerobic FN plus bottles in the detection of anaerobic organisms, we co...

journal_title：Anaerobe

authors： De Keukeleire S,Wybo I,Emmerechts K,Piérard D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND CONTEXT:Delayed-onset surgical site infections following spinal instrumentation are uncommon and often present with chronic pain and implant failure. Anaerobic organisms are rarely implicated and identified with difficulty in these infections. PURPOSE:We report a case of vertebral osteomyelitis and epidural...

journal_title：Anaerobe

authors： George IA,Pande A,Parsaei S

更新日期：2015-10-01 00:00:00

abstract：:Periodontitis is a polymicrobial anaerobe infection. Little is known about the dysbiotic microbiota and the role of bacterial metabolites in the disease process. It is suggested that the production of certain waste products in the proteolytic metabolism may work as markers for disease severity. Hydrogen sulfide (H2S) ...

journal_title：Anaerobe

authors： Basic A,Dahlén G

更新日期：2015-10-01 00:00:00

abstract：:Dental plaque is a multispecies biofilm in the oral cavity that significantly influences oral health. The presence of the oral anaerobic pathogen Porphyromonas gingivalis is an important determinant in the development of periodontitis. Direct and indirect interactions between P. gingivalis and the host play a major ro...

journal_title：Anaerobe

authors： Scheres N,Lamont RJ,Crielaard W,Krom BP

更新日期：2015-10-01 00:00:00

abstract：:Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, wh...

journal_title：Anaerobe

authors： Mackin KE,Elliott B,Kotsanas D,Howden BP,Carter GP,Korman TM,Riley TV,Rood JI,Jenkin GA,Lyras D

更新日期：2015-08-01 00:00:00

abstract：:The extracellular matrix protein fibronectin (Fn) is known to bind to the surface of Clostridium perfringens cells. Fn is a disulfide-linked homodimer protein, with each Fn polypeptide consisting of three types of repeating modules: 12 type I, 2 type II, and 15-17 type III modules. To determine the epitope on Fn recog...

journal_title：Anaerobe

authors： Katayama S,Tagomori M,Morita N,Yamasaki T,Nariya H,Okada M,Watanabe M,Hitsumoto Y

更新日期：2015-08-01 00:00:00

abstract：:Obesity is among the most pressing health concerns in the world since it is increasingly common even in the developing world, and is clearly associated with increased risk for chronic debilitating diseases and death. Furthermore, obesity can influence the pathogenesis of infectious diseases by affecting the balance of...

journal_title：Anaerobe

authors： Madan R,Petri WA Jr

更新日期：2015-08-01 00:00:00

abstract：:Post-sternotomy mediastinitis, a nosocomial infection mostly caused by staphylococci, can be life-threatening. A case of mediastinitis due to Finegoldia magna after a coronary artery bypass graft surgery was reviewed. Although this bacterium is difficult to be isolated from routine blood cultures, a F. magna bacteriem...

journal_title：Anaerobe

authors： de Moreuil C,Héry-Arnaud G,David CH,Provost B,Mondine P,Alavi Z,de Saint Martin L,Bezon E,Berre RL

更新日期：2015-04-01 00:00:00

abstract：:This study evaluated the gastrointestinal microbial diversity and the expression of pattern recognition receptors (PRRs) of the small intestine during the first week post-weaning in newly weaned piglets. Sixteen piglets were sacrificed on days 0, 1, 4, and 7 post-weaning. Luminal contents from the stomach, ileum, and ...

journal_title：Anaerobe

authors： Tao X,Xu Z,Wan J

更新日期：2015-04-01 00:00:00